His last words were "Aloha," Hawaiian for hello and goodbye.
Inouye, a Democrat from Hawaii, was hospitalized a week and a half ago at Walter Reed National Military Medical Center, where he said he was working with doctors to regulate his oxygen intake.
He is survived by his wife, Irene Hirano, and son, Daniel "Kenny" Inouye. Kenny is his son with Margaret Shinobu Awamura, to whom he was married for 56 years until her death in 2006.
Inouye had served in the Senate for 49 years, since 1963. At the time of his death, he was the longest-living serving member of the Senate. The late Sen. Robert Byrd of West Virginia is the only senator who has served longer, for 51 years.
Hawaii became a state in 1959, and Inouye was the state's first Congressman. He also became the country's first Japanese-American Congressman.
He was also hospitalized on Nov. 15 after falling and cutting the back of his head. A statement released by his office spoke to the senator’s apparent dislike of being hospitalized: “The U.S. Army Captain and World War II combat veteran wanted to put a bandage on and come to work but his family insisted he get it checked out.”
He was hospitalized the day before Pearl Harbor Day. Although ailing, he honored the day as he does every year, this time through a press release remembering his time as a Japanese-American teenager in Hawaii. He wrote: In 1941, the date December 7th was a day that evoked anger, fierce patriotism and dangerous racism. Soon after that day, I suddenly found myself, pursuant to a decision by the government and along with thousands of Japanese Americans declared 4C, enemy aliens. It was a difficult time. I was 17.
Born to working class parents, Hyotaro, a jewelry clerk, and Kame, a homemaker, Inouye dreamed of being a doctor, according to the Washington Post, plans that were sidelined by the war. He was a second-generation Japanese-American, or nisei, and he wrote that it pained him that those who dropped bombs on Hawaii looked like him.
Inouye was 17 when he enlisted in the U.S. Army and served with the 442 Regimental Combat Team, according to a statement on his website. He lost part of his right arm while he was charging a series of machine gun nests in San Terenzo, Italy.
"I looked at it, stunned and disbelieving. It dangled there by a few bloody shreds of tissue, my grenade still clenched in a fist that suddenly didn't belong to me anymore," Inouye wrote in his 1967 autobiography, "Journey to Washington," according to the Honolulu Star-Advertiser. After the war, he was nominated for the Medal of Honor but did not receive it. President Bill Clinton later bestowed the honor on him and 21 other Japanese-Americans for their courage during World War II, according to the Star-Advertiser.
